Comparison

FDA-approved, not compounded

Providers dispensing the manufacturers’ own products — Zepbound, Wegovy and the new approved pills — rather than compounded preparations.

Updated 2026-09-18

Disclosure: one company on this page — Coreage Rx — pays us a commission when a reader signs up through our link. It does not buy a better score, a higher ranking, or the removal of any criticism. The scoring rubric and the full disclosure are both published.


If you would rather not think about compounding rules, 503A licences or what is in the vial, this is the page for you. Every provider here can dispense an FDA-approved product.

It used to cost a great deal more. It still costs more than the cheapest compounded programmes, but the gap has narrowed sharply since manufacturers opened self-pay channels and two oral products launched at $149 a month.

Inclusion criteria

  • Can dispense FDA-approved branded medication, not only compounded preparations.
  • Ranked on the full rubric.
  • Note that branded medication is frequently billed separately from the programme fee.

7 of the 21 providers we track qualify. Pricing verified 2026-09-18 and re-checked periodically.

The list

#ProviderPer monthPer yearScore
1Mochi Health$278$3,3363.6
2Hims & Hers$238$2,8563.5
3Ro$448$5,3763.5
4Zealthy$216$2,5923.5
5LifeMD$149$1,7883.5
6Remedy Meds$399$4,7883.5
7WeightWatchers Clinic$74$8883.2

Cheapest qualifying option: WeightWatchers Clinic at $74 a month. Our featured partner is pinned to the top of the list where it qualifies — see how we rate for who scores higher.

1. Mochi Health — Insurance concierge support

$278 a month, including the $79 fee. Telehealth weight-care clinic with a membership model, an insurance concierge team, and compounded medication offered alongside covered branded prescriptions.

Labs are billed separately. Ask what the clinic expects to order before you sign up. Read the full Mochi Health review.

2. Hims & Hers — Widest range of formats

$238 a month, including the $39 fee. Large publicly traded telehealth platform. Sells oral kits, compounded injections and branded Zepbound side by side, with a membership required across the board.

The advertised entry prices and the membership are separate charges. Add $39/month to whatever medication figure you were quoted. Read the full Hims & Hers review.

3. Ro — Branded medication with insurance help

$448 a month, including the $149 fee. Membership-first telehealth service. Ro exited compounded GLP-1s and now routes patients to FDA-approved branded medication, billed separately from the membership.

The membership and the medication are two separate bills. A $39 first month does not mean a $39 prescription. Read the full Ro review.

4. Zealthy — Low-cost entry with insurance routing

$216 a month, no membership fee. Broad telehealth platform with a weight programme that offers both compounded medication and insurance-billed branded prescriptions.

The widely quoted $25/month is an insured price. Cash payers should plan on $151+ for semaglutide. Read the full Zealthy review.

Frequently asked

What does FDA-approved actually guarantee?

That the agency reviewed clinical trial data for safety and effectiveness, and reviewed the manufacturing process for consistency and quality. Compounded preparations have had neither review.

How much more does branded cost?

Less than it used to. Self-pay Zepbound has been listed around $299 to $499 a month, Wegovy at $199 for the first two fills through the end of 2026 and $349 after, and the approved pills from $149.

What the price does not tell you

Compounded preparations are not FDA-approved. Two approved oral GLP-1s now start around $149 a month, and from 1 July 2026 eligible Medicare beneficiaries can access certain GLP-1s for $50 a month — both of which beat a large part of this market. See the approved pills and the Medicare programme.

In SURMOUNT-1, adults with obesity lost an average of 19.5% of body weight on 10 mg and 20.9% on 15 mg over 72 weeks. That figure comes from a controlled trial of the active ingredient, not from any particular seller's product.

Read next

  • The approved pills changed the maths

    Two oral GLP-1s were approved either side of the new year, both starting at $149 a month. That undercuts a large part of the compounded market.

  • Providers that work your insurance

    Prior authorisations, appeals and coverage checks. For anyone whose plan might say yes, this is worth more than any discount.

  • Medicare, GLP-1s and the $50 month

    CMS is running a time-limited programme giving eligible Part D members certain GLP-1s for $50 a month. If you are on Medicare, read this before paying cash for anything.

  • If you will not inject

    Two FDA-approved pills launched in 2026, plus the compounded providers offering tablets and sublingual drops.