Semaglutide 2.4 mg: what it costs
Step 5 of the semaglutide ladder, around weeks 17+. 6 providers charge the same here as at the starting dose — the rest may not.
Updated 2026-09-18
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2.4 mg is step 5 of 5 on the semaglutide ladder, reached around weeks 17+. The maintenance dose for weight management, and the one behind the figure most people have read.
It is also the point where pricing starts to matter. On a programme that charges by dose, your bill climbs exactly as the treatment begins working. On a flat-rate programme, 2.4 mg costs what the starting dose cost — and over a full titration that difference is worth more than almost any advertised discount.
What 2.4 mg is for
2.4 mg is the semaglutide dose behind the figure everyone quotes: roughly 14.9% average body-weight loss over 68 weeks in STEP-1. It is the maintenance target for weight management, and for many people the end of the ladder. Worth holding onto, though: that 14.9% is an average from a controlled trial with structured support, and about 60% of weight lost is regained within a year of stopping — so the more useful question at this rung is what the long-term plan looks like, not how fast you got here.
The evidence. In STEP-1, adults on 2.4 mg lost an average of about 14.9% of body weight over 68 weeks.
This is the target for many people, but not a requirement. Settling lower and tolerating it beats reaching 2.4 mg and stopping.
Where 2.4 mg sits on the ladder
| Step | Dose | Roughly when |
|---|---|---|
| 1 | 0.25 mg | weeks 1-4 |
| 2 | 0.5 mg | weeks 5-8 |
| 3 | 1 mg | weeks 9-12 |
| 4 | 1.7 mg | weeks 13-16 |
| 5 | 2.4 mg ← this page | weeks 17+ |
What 2.4 mg costs
6 of the providers we track hold a single price at every dose, so 2.4 mg costs the same as the starting dose. They are listed first below because at this rung that is the whole ballgame.
| Provider | Price at 2.4 mg | Per year | Score |
|---|---|---|---|
| Coreage Rx | $149 | $1,788 | 4.5 |
| Trimi | $99 | $1,188 | 4.6 |
| Mochi Health | $178 | $2,136 | 3.6 |
| PlexusDx | $189 | $2,268 | 4.4 |
| Eden | $198 | $2,376 | 3.1 |
| Remedy Meds | $299 | $3,588 | 3.5 |
Cheapest flat-rate option at 2.4 mg: Trimi at $99 a month, which is what it charges at every other rung too.
The remaining 8 providers either price by dose or do not publish a flat-rate commitment. Their quoted figures start at $86 a month, but that is the starting-dose price — ask specifically what 2.4 mg will cost before you assume it holds.
Important. The question to ask before you start. "What will I be charged when I reach 2.4 mg?" If the answer is not the same number you were quoted at the start, you are on a tiered programme and should budget for the higher figure rather than the advertised one.
Do you need to go higher than 2.4 mg?
2.4 mg is the top of the ladder, so the question here is the opposite one: whether you need to stay this high. Some people step back down to a lower maintenance dose once they have reached their goal. That is a conversation for your prescriber.
What happens when I reach 2.4 mg?
For most people it becomes the ongoing maintenance dose rather than a finish line. Clinicians increasingly treat GLP-1 therapy the way they treat blood-pressure medication — something you stay on — which makes the monthly price a multi-year decision rather than a three-month one.
Compounded preparations are not FDA-approved, and approved oral GLP-1s now start around $149 — see the approved pills. Dosing belongs to your prescriber, not this page.
Read next
- Medicare, GLP-1s and the $50 month
CMS is running a time-limited programme giving eligible Part D members certain GLP-1s for $50 a month. If you are on Medicare, read this before paying cash for anything.