Semaglutide 2.4 mg: what it costs
Step 5 of the semaglutide ladder, around weeks 17+. 6 providers charge the same here as at the starting dose — the rest may not.
Updated 2026-09-18
2.4 mg sits at a specific point in the titration protocol, and what it is for differs from the rung below it.
2.4 mg is step 5 of 5 on the semaglutide ladder, reached around weeks 17+. The maintenance dose for weight management, and the one behind the figure most people have read.
It is also the point where pricing starts to matter. On a programme that charges by dose, your bill climbs exactly as the treatment begins working. On a flat-rate programme, 2.4 mg costs what the starting dose cost — and over a full titration that difference is worth more than almost any advertised discount.
What 2.4 mg is for
2.4 mg is the semaglutide dose behind the figure everyone quotes: roughly 14.9% average body-weight loss over 68 weeks in STEP-1. It is the maintenance target for weight management, and for many people the end of the ladder. Worth holding onto, though: that 14.9% is an average from a controlled trial with structured support, and about 60% of weight lost is regained within a year of stopping — so the more useful question at this rung is what the long-term plan looks like, not how fast you got here.
The evidence. In STEP-1, adults on 2.4 mg lost an average of about 14.9% of body weight over 68 weeks.
This is the target for many people, but not a requirement. Settling lower and tolerating it beats reaching 2.4 mg and stopping.
Where 2.4 mg sits on the ladder
| Step | Dose | Roughly when |
|---|---|---|
| 1 | 0.25 mg | weeks 1-4 |
| 2 | 0.5 mg | weeks 5-8 |
| 3 | 1 mg | weeks 9-12 |
| 4 | 1.7 mg | weeks 13-16 |
| 5 | 2.4 mg ← this page | weeks 17+ |
What 2.4 mg costs
6 of the providers we track hold a single price at every dose, so 2.4 mg costs the same as the starting dose. They are listed first below because at this rung that is the whole ballgame.
| Provider | Price at 2.4 mg | Per year | Score |
|---|---|---|---|
| Coreage Rx | $139 | $1,668 | 4.5 |
| Trimi | $99 | $1,188 | 4.6 |
| Mochi Health | $178 | $2,136 | 3.6 |
| PlexusDx | $189 | $2,268 | 4.4 |
| Eden | $198 | $2,376 | 3.1 |
| Remedy Meds | $299 | $3,588 | 3.5 |
Cheapest flat-rate option at 2.4 mg: Trimi at $99 a month, which is what it charges at every other rung too.
The remaining 10 providers either price by dose or do not publish a flat-rate commitment. Their quoted figures start at $85 a month, but that is the starting-dose price — ask specifically what 2.4 mg will cost before you assume it holds.
Important. The question to ask before you start. "What will I be charged when I reach 2.4 mg?" If the answer is not the same number you were quoted at the start, you are on a tiered programme and should budget for the higher figure rather than the advertised one.
Read next
- Medicare, GLP-1s and the $50 month
CMS is running a time-limited programme giving eligible Part D members certain GLP-1s for $50 a month. If you are on Medicare, read this before paying cash for anything.
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