Explainer

PlexusDx vs MEDVi

$189/mo against $399/mo for tirzepatide. Which is worth it, and for whom.

Illustration of two objects on a balance scale

Updated 2026-09-18


Both sell tirzepatide. PlexusDx costs $189 a month and MEDVi costs $399, a difference of $210 a month or about $2,520 a year. What matters more is whether the two are dispensing the same category of product at all.

PlexusDx is pharmacy transparency and genetic testing. MEDVi is tablet and injection choice. They are not aimed at the same person, and the cheaper one is not automatically the right answer — though it usually is once you have established that both dispense the same thing.

What is actually being dispensed. PlexusDx publishes which pharmacy compounds its medication; MEDVi does not. On a product the FDA has not reviewed, that is not a small difference.

Side by side

PlexusDxMEDVi
Product categoryCompounded — not FDA-approvedCompounded — not FDA-approved
Pharmacy named publiclyYesNo
Price includes the medicationYesYes
Billed monthly$189$399

Prices verified 2026-09-18. "True monthly cost" is what you are billed in month two, once any introductory rate has lapsed and any membership has renewed.

What each discloses: PlexusDx

  • Compounded semaglutide injection listed at $189/month with no membership fee and the same price at every dose.
  • A $189/month microdose tier is offered for compounded semaglutide or tirzepatide.
  • Licensed providers in all 50 states; CLIA-certified labs for its testing line.

Where it wins: The most detailed pharmacy disclosure in this comparison — six named 503A partners. Watch for: The advertised "from $129" is the programme floor. Budget $189/month for the compounded injection tier.

What each discloses: MEDVi

  • Tirzepatide tablet pricing is quoted after the intake questionnaire rather than published up front.

Where it wins: Injection pricing is consistent between the first month and renewals. Watch for: You have to complete intake before seeing tablet pricing. Injection pricing is published at $399.

Each one’s strengths

PlexusDx.

  • The most detailed pharmacy disclosure in this comparison — six named 503A partners.
  • Names its prescribing physicians along with their NPI numbers.

MEDVi.

  • Injection pricing is consistent between the first month and renewals.
  • Tablet option for people who will not inject.

PlexusDx scores higher overall at 4.4 out of 5. The weights are published on how we rate, and so is the note about which of these is our paid featured partner.

Which to choose

Decide on category first and price second. If one of these dispenses an FDA-approved product and the other a compounded preparation, you are not comparing like with like at any price. Where both are compounded, the pharmacy disclosure row is the next thing to weigh.

The verdict

On price alone, PlexusDx at $189 a month is the more defensible choice on arithmetic alone. MEDVi earns its premium only if you will actually use what it does differently. Read the full reviews before deciding: PlexusDx and MEDVi.

How they sit against everyone else

Dispensed byProductPer monthScore
Coreage Rx
Best overall on true monthly cost
Compounded$1994.5
SuperHealthy Rx
Public offer; not independently scored
Compounded$135Not scored
Likeness Rx
Public offer; not independently scored
Compounded$199Not scored
Trimi
Lowest flat price with named pharmacies
Compounded$1254.6
PlexusDx
Pharmacy transparency and genetic testing
Compounded$1894.4
Ozari Health
Lowest advertised semaglutide price
Compounded$1254.4
Fifty 410
Prepaid blocks with no subscription
Compounded$1334.2
Ivím Health
Unlimited clinician access
Compounded$1994
Mochi Health
Insurance concierge support
Compounded$278
+$79 fee
3.6
Coby Health
Multi-month value with supplies included
Compounded$2393.6
Hims & Hers
Widest range of formats
Compounded$238
+$39 fee
3.5
Ro
Branded medication with insurance help
FDA-approved brand$448
+$149 fee
3.5

Read next

  • PlexusDx tirzepatide review

    Pharmacy transparency and genetic testing. What is actually dispensed, how the prescription works, and what the price really is — $189 a month.

  • MEDVi tirzepatide review

    Tablet and injection choice. What is actually dispensed, how the prescription works, and what the price really is — $399 a month.

  • How to spot a bad seller

    The FDA sent more than 55 warning letters to online GLP-1 sellers in one day. Here is how to tell a licensed programme from the rest.

  • The twelve-month cost

    Month one is the cheapest month you will have. Here is the full-year arithmetic, including the costs nobody puts in the advert.

  • Tirzepatide programmes compared

    23 programmes side by side — what each dispenses, under what authority, and what it really costs.

Coreage Rx pays us a commission on sign-ups through our links. It does not affect our scores or rankings. How we rate · Disclosure