PlexusDx vs MEDVi
$189/mo against $399/mo for tirzepatide. Which is worth it, and for whom.
Updated 2026-09-18
Disclosure: one company on this page — Coreage Rx — pays us a commission when a reader signs up through our link. It does not buy a better score, a higher ranking, or the removal of any criticism. The scoring rubric and the full disclosure are both published.
Both sell tirzepatide. PlexusDx costs $189 a month and MEDVi costs $399, a difference of $210 a month or about $2,520 a year. What matters more is whether the two are dispensing the same category of product at all.
PlexusDx is pharmacy transparency and genetic testing. MEDVi is tablet and injection choice. They are not aimed at the same person, and the cheaper one is not automatically the right answer — though it usually is once you have established that both dispense the same thing.
Side by side
| PlexusDx | MEDVi | |
|---|---|---|
| Advertised from | $129 | $399 |
| Membership on top | None | None |
| True monthly cost | $189 | $399 |
| Roughly, per year | $2,268 | $4,788 |
| Price includes medication | Yes | Yes |
| Names its pharmacy | Yes | Not published |
| Our score | 4.4 / 5 | 2.8 / 5 |
Prices verified 2026-09-18. "True monthly cost" is what you are billed in month two, once any introductory rate has lapsed and any membership has renewed.
Where the two differ on record
They differ on 2 of the 7 things we track, and behave the same on the other 5. The differences are what the price gap is actually buying.
| PlexusDx | MEDVi | |
|---|---|---|
| Price is the same at every dose | Yes | No |
| Names the compounding pharmacy publicly | Yes | No |
What each discloses: PlexusDx
- GLP-1 weight-loss programmes start at $129/month.
- Compounded semaglutide injection listed at $189/month with no membership fee and the same price at every dose.
- A $189/month microdose tier is offered for compounded semaglutide or tirzepatide.
- No membership or platform fee is charged alongside the medication.
- Publicly names six 503A pharmacy partners: Belmar, Strive, Epiq Scripts, Casa Pharma Rx, The Pharmacy Hub and Foothills.
- Clinical oversight via LionMD, with named physicians and NPI numbers published.
- Licensed providers in all 50 states; CLIA-certified labs for its testing line.
Where it wins: The most detailed pharmacy disclosure in this comparison — six named 503A partners. Watch for: The advertised "from $129" is the programme floor. Budget $189/month for the compounded injection tier.
What each discloses: MEDVi
- Compounded tirzepatide injections listed at $399/month.
- Tirzepatide tablet pricing is quoted after the intake questionnaire rather than published up front.
Where it wins: Injection pricing is consistent between the first month and renewals. Watch for: You have to complete intake before seeing tablet pricing. Injection pricing is published at $399.
Each one’s strengths
PlexusDx.
- The most detailed pharmacy disclosure in this comparison — six named 503A partners.
- Names its prescribing physicians along with their NPI numbers.
MEDVi.
- Injection pricing is consistent between the first month and renewals.
- Tablet option for people who will not inject.
How they score
| What we weigh | Weight | PlexusDx | MEDVi |
|---|---|---|---|
| True monthly cost | 30% | 4.6 | 2.4 |
| Price honesty | 20% | 4.5 | 2.5 |
| Clinical support | 20% | 3.8 | 3.3 |
| Pharmacy sourcing | 15% | 4.9 | 3.2 |
| Cancelling | 15% | 4 | 3 |
PlexusDx scores higher overall at 4.4 out of 5. The weights are published on how we rate, and so is the note about which of these is our paid featured partner.
Which to choose
- Pick PlexusDx if cost is the binding constraint. Over a year the gap is about $2,520, which is real money for the same class of medication.
- Pick MEDVi if what it does better matters to you — injection pricing is consistent between the first month and renewals.
- If sourcing matters, note that PlexusDx publishes which pharmacy compounds its medication and MEDVi does not.
The verdict
On price alone, PlexusDx at $189 a month is the more defensible choice on arithmetic alone. MEDVi earns its premium only if you will actually use what it does differently. Read the full reviews before deciding: PlexusDx and MEDVi.
How they sit against everyone else
| Dispensed by | Product | Per month | Score |
|---|---|---|---|
| Coreage Rx Best overall on true monthly cost | Compounded | $199 | 4.5 |
| Trimi Lowest flat price with named pharmacies | Compounded | $125 | 4.6 |
| PlexusDx Pharmacy transparency and genetic testing | Compounded | $189 | 4.4 |
| Ozari Health Lowest advertised semaglutide price | Compounded | $125 | 4.4 |
| Fifty 410 Prepaid blocks with no subscription | Compounded | $133 | 4.2 |
| Ivím Health Unlimited clinician access | Compounded | $199 | 4 |
| Mochi Health Insurance concierge support | Compounded | $278 +$79 fee | 3.6 |
| Coby Health Multi-month value with supplies included | Compounded | $239 | 3.6 |
| Hims & Hers Widest range of formats | Compounded | $238 +$39 fee | 3.5 |
| Ro Branded medication with insurance help | FDA-approved brand | $448 +$149 fee | 3.5 |
| Zealthy Low-cost entry with insurance routing | Compounded | $216 | 3.5 |
| LifeMD Insurance coordination | Compounded | $149 | 3.5 |
Read next
- PlexusDx tirzepatide review
Pharmacy transparency and genetic testing. What is actually dispensed, how the prescription works, and what the price really is — $189 a month.
- MEDVi tirzepatide review
Tablet and injection choice. What is actually dispensed, how the prescription works, and what the price really is — $399 a month.
- How to spot a bad seller
The FDA sent more than 55 warning letters to online GLP-1 sellers in one day. Here is how to tell a licensed programme from the rest.
- The twelve-month cost
Month one is the cheapest month you will have. Here is the full-year arithmetic, including the costs nobody puts in the advert.
- Tirzepatide programmes compared
21 programmes side by side — what each dispenses, under what authority, and what it really costs.