PlexusDx vs Willow
$189/mo against $399/mo for tirzepatide. Which is worth it, and for whom.
Updated 2026-09-18
Both sell tirzepatide. PlexusDx costs $189 a month and Willow costs $399, a difference of $210 a month or about $2,520 a year. What matters more is whether the two are dispensing the same category of product at all.
PlexusDx is pharmacy transparency and genetic testing. Willow is straightforward single-price plans. They are not aimed at the same person, and the cheaper one is not automatically the right answer — though it usually is once you have established that both dispense the same thing.
What is actually being dispensed. PlexusDx publishes which pharmacy compounds its medication; Willow does not. On a product the FDA has not reviewed, that is not a small difference.
Side by side
| PlexusDx | Willow | |
|---|---|---|
| Product category | Compounded — not FDA-approved | Compounded — not FDA-approved |
| Pharmacy named publicly | Yes | No |
| Price includes the medication | Yes | Yes |
| Billed monthly | $189 | $399 |
Prices verified 2026-09-18. "True monthly cost" is what you are billed in month two, once any introductory rate has lapsed and any membership has renewed.
What each discloses: PlexusDx
- Compounded semaglutide injection listed at $189/month with no membership fee and the same price at every dose.
- A $189/month microdose tier is offered for compounded semaglutide or tirzepatide.
- Licensed providers in all 50 states; CLIA-certified labs for its testing line.
Where it wins: The most detailed pharmacy disclosure in this comparison — six named 503A partners. Watch for: The advertised "from $129" is the programme floor. Budget $189/month for the compounded injection tier.
What each discloses: Willow
Where it wins: A single price with no membership arithmetic. Watch for: There is little published detail on how dose changes are handled. Ask before committing.
Each one’s strengths
PlexusDx.
- The most detailed pharmacy disclosure in this comparison — six named 503A partners.
- Names its prescribing physicians along with their NPI numbers.
Willow.
- A single price with no membership arithmetic.
PlexusDx scores higher overall at 4.4 out of 5. The weights are published on how we rate, and so is the note about which of these is our paid featured partner.
Which to choose
Decide on category first and price second. If one of these dispenses an FDA-approved product and the other a compounded preparation, you are not comparing like with like at any price. Where both are compounded, the pharmacy disclosure row is the next thing to weigh.
The verdict
On price alone, PlexusDx at $189 a month is the more defensible choice on arithmetic alone. Willow earns its premium only if you will actually use what it does differently. Read the full reviews before deciding: PlexusDx and Willow.
How they sit against everyone else
| Dispensed by | Product | Per month | Score |
|---|---|---|---|
| Coreage Rx Best overall on true monthly cost | Compounded | $199 | 4.5 |
| SuperHealthy Rx Public offer; not independently scored | Compounded | $135 | Not scored |
| Likeness Rx Public offer; not independently scored | Compounded | $199 | Not scored |
| Trimi Lowest flat price with named pharmacies | Compounded | $125 | 4.6 |
| PlexusDx Pharmacy transparency and genetic testing | Compounded | $189 | 4.4 |
| Ozari Health Lowest advertised semaglutide price | Compounded | $125 | 4.4 |
| Fifty 410 Prepaid blocks with no subscription | Compounded | $133 | 4.2 |
| Ivím Health Unlimited clinician access | Compounded | $199 | 4 |
| Mochi Health Insurance concierge support | Compounded | $278 +$79 fee | 3.6 |
| Coby Health Multi-month value with supplies included | Compounded | $239 | 3.6 |
| Hims & Hers Widest range of formats | Compounded | $238 +$39 fee | 3.5 |
| Ro Branded medication with insurance help | FDA-approved brand | $448 +$149 fee | 3.5 |
Read next
- PlexusDx tirzepatide review
Pharmacy transparency and genetic testing. What is actually dispensed, how the prescription works, and what the price really is — $189 a month.
- Willow tirzepatide review
Straightforward single-price plans. What is actually dispensed, how the prescription works, and what the price really is — $399 a month.
- How to spot a bad seller
The FDA sent more than 55 warning letters to online GLP-1 sellers in one day. Here is how to tell a licensed programme from the rest.
- The twelve-month cost
Month one is the cheapest month you will have. Here is the full-year arithmetic, including the costs nobody puts in the advert.
- Tirzepatide programmes compared
23 programmes side by side — what each dispenses, under what authority, and what it really costs.
Coreage Rx pays us a commission on sign-ups through our links. It does not affect our scores or rankings. How we rate · Disclosure