Trimi vs Fifty 410

Both sell tirzepatide. Trimi costs $125 a month and Fifty 410 costs $133, a difference of $8 a month or about $96 a year. What matters more is whether the two are dispensing the same category of product at all.

Trimi is lowest flat price with named pharmacies. Fifty 410 is prepaid blocks with no subscription. They are not aimed at the same person, and the cheaper one is not automatically the right answer — though it usually is once you have established that both dispense the same thing.

What is actually being dispensed. Trimi publishes which pharmacy compounds its medication; Fifty 410 does not. On a product the FDA has not reviewed, that is not a small difference.

Side by side

Prices verified 2026-09-18. "True monthly cost" is what you are billed in month two, once any introductory rate has lapsed and any membership has renewed.

What each discloses: Trimi

• Compounded semaglutide advertised at $99/month on the annual plan.
• Price is the same at every prescribed dose.
• Advertises a six-month money-back promise subject to terms.

Where it wins: The cheapest verified flat rate for compounded tirzepatide in this comparison. Watch for: Both headline prices are annual-plan rates. Confirm the month-to-month figure and the refund terms before prepaying twelve months.

What each discloses: Fifty 410

• High-dose tirzepatide protocol at $183/month, sold as a $549 three-month block.
• No membership, no subscription and no recurring charges — you buy a block outright.
• No payment taken unless a provider approves you.

Where it wins: Genuinely no subscription — you buy a block and nothing recurs. Watch for: The $133 is the starter protocol. Moving to the high-dose protocol takes it to $183/month, and both are prepaid three-month commitments.

Each one’s strengths

Trimi.

• The cheapest verified flat rate for compounded tirzepatide in this comparison.
• Names its pharmacies with a licence number and offers a certificate of analysis — almost nobody else in this market does.

Fifty 410.

• Genuinely no subscription — you buy a block and nothing recurs.
• Among the lowest tirzepatide rates verified.

Trimi scores higher overall at 4.6 out of 5. The weights are published on how we rate, and so is the note about which of these is our paid featured partner.

Which to choose

Decide on category first and price second. If one of these dispenses an FDA-approved product and the other a compounded preparation, you are not comparing like with like at any price. Where both are compounded, the pharmacy disclosure row is the next thing to weigh.

The verdict

On price alone, Trimi at $125 a month is the more defensible choice on arithmetic alone. Fifty 410 earns its premium only if you will actually use what it does differently. Read the full reviews before deciding: Trimi and Fifty 410.

How they sit against everyone else